1. What is the Rituximab 375 mg/m² Calculator?

Definition: This calculator determines the appropriate dose of Rituximab based on a patient's body surface area (BSA) using the standard 375 mg/m² dosing regimen.

Purpose: It helps healthcare professionals accurately calculate Rituximab doses for patients undergoing treatment for conditions like non-Hodgkin's lymphoma or rheumatoid arthritis.

2. How Does the Calculator Work?

The calculator uses the formula:

Where:

• \( \text{Dose} \) — Rituximab dose in milligrams (mg)
• \( \text{BSA} \) — Body Surface Area in square meters (m²)

Explanation: The standard Rituximab dosing regimen is 375 mg per square meter of body surface area, which accounts for patient size while maintaining therapeutic effectiveness.

3. Importance of Accurate Rituximab Dosing

Details: Proper dosing ensures therapeutic efficacy while minimizing potential side effects. BSA-based dosing helps standardize treatment across patients of different sizes.

4. Using the Calculator

Tips: Enter the patient's BSA in m² (must be > 0). The calculator will compute the appropriate Rituximab dose in milligrams.

5. Frequently Asked Questions (FAQ)

Q1: What is the standard Rituximab dosing regimen?
A: The standard dose is 375 mg/m², typically administered weekly for 4-8 doses depending on the condition being treated.

Q2: How is BSA calculated?
A: BSA is commonly calculated using the Mosteller formula: √(height in cm × weight in kg / 3600).

Q3: Are there any maximum dose limits?
A: Some protocols may specify maximum doses, but this calculator follows the standard 375 mg/m² formula without upper limits.

Q4: Can this calculator be used for pediatric patients?
A: Yes, the 375 mg/m² regimen can be used for pediatric patients, though specific protocols may vary.

Q5: Does this account for renal or hepatic impairment?
A: No, consult specific guidelines for dose adjustments in patients with organ dysfunction.