Chemotherapy Dose Formula:
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Definition: This calculator determines the appropriate chemotherapy dose based on body surface area (BSA) and the drug-specific dose per square meter.
Purpose: It helps healthcare professionals calculate precise chemotherapy doses tailored to individual patient size.
The calculator uses the formula:
Where:
Explanation: The drug-specific dose per square meter is multiplied by the patient's BSA to determine the total dose.
Details: BSA-based dosing helps standardize chemotherapy administration, accounting for patient size while minimizing toxicity risks.
Tips: Enter the drug's dose per m² (from protocol) and the patient's BSA (calculated separately). Both values must be > 0.
Q1: How is BSA typically calculated?
A: BSA is commonly calculated using the Mosteller formula: √(height in cm × weight in kg / 3600).
Q2: Why use BSA instead of weight alone?
A: BSA correlates better with metabolic rate and drug clearance than weight alone, especially for cytotoxic drugs.
Q3: Are there exceptions to BSA dosing?
A: Yes, some drugs have maximum dose limits or are dosed differently (e.g., flat dosing, AUC-based).
Q4: How precise should the dose be?
A: Chemo doses are typically rounded to the nearest whole number for safety and practicality.
Q5: Should I adjust for obese patients?
A: Some protocols use adjusted body weight or cap BSA at 2.0 m² - always follow specific protocol guidelines.