Mosteller Formula:
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Definition: Body Surface Area (BSA) is a measurement used in chemotherapy dosing to calculate the appropriate drug amount based on a patient's size.
Purpose: BSA helps determine chemotherapy drug doses that are more accurate than weight-based dosing alone, reducing toxicity risks.
The calculator uses the Mosteller formula:
Where:
Explanation: The formula calculates the approximate surface area of a human body based on weight and height.
Details: BSA-based dosing helps standardize chemotherapy administration, accounting for metabolic differences between patients of different sizes.
Tips: Enter the patient's weight in kilograms and height in centimeters. Both values must be > 0.
Q1: Why use BSA instead of weight alone for chemotherapy?
A: BSA better correlates with metabolic processes and drug clearance than weight alone, leading to more accurate dosing.
Q2: What's the range of normal BSA values?
A: Average BSA is about 1.7 m² for adult men and 1.6 m² for adult women, but varies with body size.
Q3: Are there other BSA formulas?
A: Yes, including DuBois, Haycock, and Boyd formulas, but Mosteller is most commonly used in clinical practice.
Q4: How precise should BSA calculations be?
A: Typically rounded to 2 decimal places for chemotherapy dosing.
Q5: Does BSA calculation differ for children?
A: The same formula is used, but pediatric dosing may incorporate additional factors like age and developmental stage.